Slicers like PrusaSlicer, Bambu Studio, OrcaSlicer, and Cura have wonderful "auto" features, particularly for supports. But they are guessing.
An auto-support algorithm doesn't know that the ugly interface layer will be right on the face of your highly detailed statue. It doesn't know that you need the bolt hole to be perfectly clean.
Learning to manually paint supports allows you to place material exactly where it’s needed and, more importantly, block supports from areas where they will ruin the surface finish.
Similarly, "Generic PLA" profiles are safe baselines, not optimal settings. Tuning your retraction settings and cooling fan speeds for your specific brand of filament is often the difference between a "good" print and a "factory-molded" quality part.